Simşek Aykin, Senköylü Alpaslan, Cila Erdal, Uğurlu Mahmut, Bayar Ahmet, Oztürk Akif M, Işikli Sedat, Muşdal Yasin, Yetkin Haluk
Gazi Universitesi Tip Fakültesi Ortopedi ve Travmatoloji Anabilim Dali.
Acta Orthop Traumatol Turc. 2006;40(2):140-3.
Trace elements zinc and copper are effective in wound and fracture healing. In this prospective study, correlations between mangled extremity severity score (MESS) and mangled extremity syndrome index (MESI) and serum zinc and copper levels were investigated in trauma patients.
Seventeen trauma patients (11 females, 6 males; mean age 41.6 years; range 11 to 73 years) were evaluated with respect to MESS and MESI scores. On the seventh day of trauma, serum samples were obtained to determine zinc and copper levels by atomic absorption spectrophotometry.
Serum levels of zinc and copper showed significant negative correlations with both MESS (r=-0.65 and r=-0.76, respectively) and MESI (r=-0.83 and r=-0.77, respectively) scores (p<0.05).
The severity of trauma is associated with significant decreases in serum levels of trace elements. Thus, trace element supplementation may be an important aspect of treatment in trauma patients.
微量元素锌和铜在伤口愈合及骨折愈合中具有显著疗效。在这项前瞻性研究中，对创伤患者的肢体毁损严重程度评分（MESS）、肢体毁损综合征指数（MESI）与血清锌和铜水平之间的相关性进行了研究。
对17例创伤患者（11例女性，6例男性；平均年龄41.6岁；年龄范围11至73岁）进行了MESS和MESI评分评估。在创伤发生后的第7天，采集血清样本，采用原子吸收分光光度法测定锌和铜水平。
血清锌和铜水平与MESS评分（分别为r = -0.65和r = -0.76）及MESI评分（分别为r = -0.83和r = -0.77）均呈显著负相关（p < 0.05）。
创伤的严重程度与血清微量元素水平的显著降低相关。因此，补充微量元素可能是创伤患者治疗的一个重要方面。
Zotero 插件