Karkuzhali P, Deiveegan K
Department of Neuropathology, Institute of Neurology, Madras Medical College, Chennai - 3.
Indian J Pathol Microbiol. 2005 Apr;48(2):243-4.
A case of 7 yr old boy with cerebellar melanotic medulloblastoma is reported. Melanotic medulloblastoma is a variant of medulloblastoma, which shares some of the histological features of Melanotic neuroectodermal tumor of infancy. However the predominant histological pattern and clinical behavior is that of conventional or classical medulloblastoma. The melanin pigments present in these tumors have been proved to be both neuromelanin and oculocutaneous type of melanin. This is a rare histological type and only few cases have been reported in the literature so far.
报告了一例7岁男孩患小脑黑色素性髓母细胞瘤的病例。黑色素性髓母细胞瘤是髓母细胞瘤的一种变体,它具有婴儿黑色素性神经外胚层肿瘤的一些组织学特征。然而,其主要的组织学模式和临床行为与传统或经典髓母细胞瘤相同。这些肿瘤中存在的黑色素已被证明既有神经黑色素,也有眼皮肤型黑色素。这是一种罕见的组织学类型,迄今为止文献中仅报道了少数病例。