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[大肠杆菌——败血症中被遗忘的病原体]

[Escherichia coli a forgotten pathogen in septicemia].

作者信息

Sledzińska Anna, Samet Alfred, Bronk Marek, Rybak Bartosz, Kur Józef, Krawczyk Beata, Nowicki Bogdan

机构信息

Laboratorium Mikrobiologii Klinicznej Samodzielnego Publicznego Szpitala Klinicznego nrl Akademickie Centrum Kliniczne Akademii Medycznej w Gdańsku.

出版信息

Przegl Epidemiol. 2006;60(1):27-34.

PMID:16758735
Abstract

The aim of the retrospect study was to analyse the incidence of E. coli bacteremia in eight wards of SPSK 1 ACK AM in Gdansk from 2002 to 2004. We analyzed the incidence of bacteremia, patients outcome, source of infection and antimicrobial susceptibility. During the study period we detected 268 patients with E. coli bacteremia (8,0% of all bacteremic patients). 11,2% of them died within 24-48h after positive blood culture. Incidence of bacteremia was 1,7/1000 patients and the highest level achieved in Hematology Unit--33,2. The main portal of entry was genitourinary tract (24,3%) and gastrointestinal tract (21,8%). The strains (n=263) were least susceptible to ampicillin (33,3%), co-trimoxazole (68,4%), amoxycillin with clavulanic acid (69,3%) and ciprofloxacine (78,9%).

摘要

这项回顾性研究的目的是分析2002年至2004年期间格但斯克市SPSK 1 ACK AM的八个病房中大肠杆菌菌血症的发病率。我们分析了菌血症的发病率、患者的预后、感染源以及抗菌药物敏感性。在研究期间,我们检测到268例大肠杆菌菌血症患者(占所有菌血症患者的8.0%)。其中11.2%的患者在血培养阳性后的24至48小时内死亡。菌血症的发病率为1.7/1000例患者,血液科的发病率最高,达到33.2/1000例患者。主要的感染途径是泌尿生殖道(24.3%)和胃肠道(21.8%)。这些菌株(n = 263)对氨苄西林(33.3%)、复方新诺明(68.4%)、阿莫西林克拉维酸(69.3%)和环丙沙星(78.9%)的敏感性最低。

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