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[胺碘酮肺炎合并超鞭毛虫肺部感染:一例报告及文献复习]

[Amiodarone pneumonitis with Hypermastigote lung infection: a case report and review of the literatures].

作者信息

Nie Xiao-meng, Yao Xiao-peng, Huang Yi, Zhou Dao-yin, Chang Zheng-shan, Li Qiang

机构信息

Department of Respiratory Medicine, Changhai Hospital, Second Military Medical University, Shanghai 200433, China.

出版信息

Zhonghua Jie He He Hu Xi Za Zhi. 2006 May;29(5):310-2.

Abstract

OBJECTIVE

To describe the clinical features of amiodarone pneumonitis with Hypermastigote lung infection.

METHODS

Case report and review of the related literatures. The clinical symptoms, laboratory tests, radiographic patterns, diagnosis, and therapeutic management of amiodarone pneumonitis with Hypermastigote lung infection were described.

RESULTS

A 58 year old male patient presented dyspnea after exertion. Pulmonary function showed decrease of the diffusing capacity, and CT showed interstitial changes and alveolar exudation. Foamy cells and Hypermastigotes were found in the bronchoalveolar lavage fluid. After cessation of amiodarone and the start of anti-parasite therapy, the symptoms relieved.

CONCLUSIONS

Amiodarone pneumonitis with Hypermastigote lung infection is very rare. The infection may be due to decrease of local immunity caused by amiodarone pneumonitis.

摘要

目的

描述合并超鞭毛虫肺部感染的胺碘酮肺炎的临床特征。

方法

病例报告及相关文献复习。描述了合并超鞭毛虫肺部感染的胺碘酮肺炎的临床症状、实验室检查、影像学表现、诊断及治疗处理。

结果

一名58岁男性患者出现劳力性呼吸困难。肺功能显示弥散功能下降,CT显示间质改变和肺泡渗出。支气管肺泡灌洗液中发现泡沫细胞和超鞭毛虫。停用胺碘酮并开始抗寄生虫治疗后,症状缓解。

结论

合并超鞭毛虫肺部感染的胺碘酮肺炎非常罕见。感染可能是由于胺碘酮肺炎导致局部免疫力下降所致。

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