Iacobellis Gianluca, Leonetti Frida, Singh Navneet, M Sharma Arya
Int J Cardiol. 2007 Feb 7;115(2):272-3. doi: 10.1016/j.ijcard.2006.04.016. Epub 2006 Jun 8.
Obesity is associated with atrial dilation and diastolic dysfunction although the causative mechanisms are not completely understood. In this study we showed for the first time that increase in epicardial fat thickness is significantly correlated with atria enlargement and impairment in diastolic filling in morbidly obese subjects.
肥胖与心房扩张和舒张功能障碍有关,尽管其致病机制尚未完全明确。在本研究中,我们首次表明,病态肥胖受试者的心外膜脂肪厚度增加与心房扩大及舒张期充盈受损显著相关。