Dechev Ivan Y, Banchev Angel V, Mateva Nonka G
Department of Urology, Medical University, Plovdiv, 15A Vassil Aprilov St., 4002 Plovdiv, Bulgaria.
Folia Med (Plovdiv). 2005;47(3-4):33-9.
Carcinoma of the penis is a malignant tumour which is uncommon in the male population of the Plovdiv, Pazardzhik and Smolyan regions. Recently however, its occurrence in the clinical practice has been on the increase. In the present study we analyse the incidence of penile carcinoma in these regions and address some problems related to late diagnosing of the condition and its therapy.
The study included fifty one patients newly diagnosed with carcinoma of the penis between 1993 and 2002. The patients were registered in the Plovdiv Oncological Centre database. The available data were studied in detail analysing the incidence and mortality rates of the disease.
The incidence and mortality rates carried by carcinoma of the penis showed a tendency to simultaneous increase with time--by 0.1355 and 0.0392 per 100000 men per annum, respectively. There is a relatively high number of patients diagnosed with carcinoma of the penis in the stage of invasive local tumor (82.35%). The distribution of the cases by stages is highly unfavourable--over 33% of them were diagnosed very late (stage III and IV). The greatest number of cases (70.59%) received only surgical treatment. The 5-year survival rate of the diagnosed patients is only 58.86%.
These data about the incidence of the disease and the diagnosis and treatment of penile cancer in the studied regions are indicative of highly unfavourable tendencies for this disease which are reflected in the low efficaciousness of cancer control in the studied localisation.
阴茎癌是一种恶性肿瘤,在普罗夫迪夫、帕扎尔吉克和斯莫梁地区的男性人群中并不常见。然而,最近其在临床实践中的发生率一直在上升。在本研究中,我们分析了这些地区阴茎癌的发病率,并探讨了与该病晚期诊断及其治疗相关的一些问题。
该研究纳入了1993年至2002年间新诊断为阴茎癌的51例患者。这些患者被登记在普罗夫迪夫肿瘤中心数据库中。对现有数据进行了详细研究,分析了该疾病的发病率和死亡率。
阴茎癌的发病率和死亡率呈现出随时间同时上升的趋势——每年每10万名男性中分别上升0.1355和0.0392。在浸润性局部肿瘤阶段被诊断为阴茎癌的患者数量相对较多(82.35%)。病例按阶段分布非常不利——超过33%的患者被诊断时已处于晚期(III期和IV期)。大多数病例(70.59%)仅接受了手术治疗。确诊患者的5年生存率仅为58.86%。
这些关于所研究地区该疾病发病率以及阴茎癌诊断和治疗的数据表明,这种疾病存在非常不利的趋势,这反映在所研究部位癌症控制的低效性上。