Lodén M, Lindberg M
Medical Department, ACO AB, University Hospital, Uppsala, Sweden.
Acta Derm Venereol. 1991;71(1):79-82.
Moisturizers are believed to improve the skin condition by increasing the water content of the stratum corneum. A variety of techniques for assessing skin hydration has been developed. In the present study the capacitance following a single application of different moisturizers to normal skin on 12 volunteers was measured with the commercial available Corneometer 420. The moisturizers were pure petrolatum and three oil-in-water creams. The latter contained either glycerine, glycerine and pyrollidone carboxylic acid, or urea as humectant agents. The first measurement of the change in the capacitance was done 2 h after application of the products. All tested products increased the capacitance in the same order of magnitude. For the creams the values were significantly enhanced during the experimental period (6 h). Excess product were removed from some skin areas after the 2 h measurement. This caused immediately a significant decrease in the capacitance of the cream treated sites, whereas a tendency towards higher values were noted on the petrolatum-treated sites. These findings indicate that the non-absorbed components influences the capacitance values. Hence, the interpretation of electrical measurements with respect to skin moisture should be made with caution.
人们认为保湿剂通过增加角质层的含水量来改善皮肤状况。已经开发出多种评估皮肤水合作用的技术。在本研究中,使用市售的Corneometer 420测量了12名志愿者正常皮肤上单次涂抹不同保湿剂后的电容。保湿剂为纯凡士林和三种水包油乳膏。后者含有甘油、甘油和吡咯烷酮羧酸或尿素作为保湿剂。在涂抹产品2小时后首次测量电容变化。所有测试产品使电容增加的幅度相同。对于乳膏,在实验期间(6小时)其值显著提高。在2小时测量后,从一些皮肤区域去除多余的产品。这立即导致乳膏处理部位的电容显著下降,而在凡士林处理部位则注意到有值升高的趋势。这些发现表明未吸收的成分会影响电容值。因此,在解释关于皮肤水分的电学测量结果时应谨慎。