Gopalakrishnan P, Miller J E, McLaughlin J S
Am Surg. 1975 Jul;41(7):405-8.
Of 7,986 patients admitted to Mount Wilson State Hospital for Pulmonary Diseases between 1960 and 1970, 72 were proven to have coexisting pulmonary tuberculosis and bronchogenic carcinoma. The patients usually were in the older age group, and usually smoked. There was a high predilection for the tumor to occur in the upper lobes. Active tuberculosis was present in 50 per cent of the patients and tumor and tuberculosis was present in the same area 80 per cent of the time. Cell diagnosis was possible in 60 per cent of the patients without thoracotomy. Diagnosis was usually made late in the course of the disease and therapeutic results were poor. Only 13 patients were operable and only four are presently alive. Earlier recognition is vital to adequate treatment. A plan for earlier recognition based on a high degree of suspicion is presented.
1960年至1970年间,威尔逊山州立肺病医院收治了7986名患者,其中72人被证实同时患有肺结核和支气管源性癌。这些患者通常年龄较大,且通常有吸烟习惯。肿瘤高度倾向于发生在上叶。50%的患者存在活动性肺结核,80%的情况下肿瘤和肺结核出现在同一区域。60%的患者无需开胸即可进行细胞诊断。诊断通常在疾病晚期做出,治疗效果不佳。只有13名患者可进行手术,目前只有4人存活。早期识别对于充分治疗至关重要。本文提出了一项基于高度怀疑的早期识别计划。