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《结节病性眼病诊断指南》中结节病眼部表现分类的重新评估

[The reevaluation of categorization for ocular manifestation of sarcoidosis in the "Guidelines for Diagnosis of Ocular Sarcoidosis"].

作者信息

Asukata Yuri, Ishihara Mami, Nakamura Satoshi, Hayashi Kiyofumi, Itoh Yoshiki, Takiyama Naoaki, Mizuki Nobuhisa

机构信息

Department of Ophthalmology and Visual Science, Yokohama City University School of Medicine, Japan.

出版信息

Nippon Ganka Gakkai Zasshi. 2006 May;110(5):391-7.

Abstract

PURPOSE

To increase the degree of specificity for nomenclature in the current "Guidelines for Diagnosis of Ocular Sarcoidosis" published in 1990 by the Diffuse Pulmonary Disease Research Committee of Japan.

SUBJECTS AND METHODS

We reviewed the records of patients with uveitis from the Uveitis Clinic in the Department of Ophthalmology at Yokohama City University. Subjects were selected from the records of uveitis patients with histologically proven sarcoidosis (78), and others with non-sarcoidosis uveitis (81). We examined the sensitivity and specificity of suspected characteristics of ocular sarcoidosis in the current "Guidelines for Diagnosis of Ocular Sarcoidosis".

RESULTS

The definition specificity was improved by changing anterior uveitis to granulomatous anterior uveitis, and by simplifying to cloudy mass (snowball, string of pearls) from the previous diffused/cloudy mass vitreous opacity (snowball, string of pearls), and also by changing from retinal peripheral vasculitis (in many cases retinal periphlebitis, also at times retinal peripheral arteritis) to retinal periphlebitis.

CONCLUSION

This newly proposed "Guidelines for Diagnosis of Ocular Sarcoidosis" gives a much clearer definition of sarcoidosis, as well as improved nomenclature for specific categories of ocular symptoms.

摘要

目的

提高日本弥漫性肺疾病研究委员会于1990年发布的现行《眼部结节病诊断指南》中命名的特异性程度。

对象与方法

我们回顾了横滨市立大学眼科葡萄膜炎诊所葡萄膜炎患者的病历。研究对象从经组织学证实为结节病的葡萄膜炎患者(78例)以及其他非结节病性葡萄膜炎患者(81例)的病历中选取。我们检查了现行《眼部结节病诊断指南》中眼部结节病疑似特征的敏感性和特异性。

结果

通过将前葡萄膜炎改为肉芽肿性前葡萄膜炎,将之前的弥漫性/云雾状玻璃体混浊(雪球状、珍珠串状)简化为云雾状肿物(雪球状、珍珠串状),以及将视网膜周边血管炎(在许多情况下为视网膜静脉周围炎,有时也为视网膜周边动脉炎)改为视网膜静脉周围炎,定义的特异性得到了提高。

结论

这份新提出的《眼部结节病诊断指南》对结节病给出了更清晰的定义,同时改进了特定类别眼部症状的命名。

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