使用特制冷冻探头进行二尖瓣疾病合并心房颤动的肺静脉口冷冻消融术
[Pulmonary vein orifice cryoablation for atrial fibrillation with mitral valve disease using a specially designed cryo-probe].
作者信息
Furukawa Hiroshi, Konishi Toshio, Fukata Mutsumu, Okura Kazuhiro
机构信息
Department of Cardiovascular Surgery, Yokohama Rosai Hospital, Yokohama.
出版信息
J Cardiol. 2006 May;47(5):239-43.
OBJECTIVES
To evaluate the effectiveness of pulmonary vein orifice cryoablation (PVOC) for atrial fibrillation during mitral valve surgery.
METHODS
Twenty-two patients (12 men and 10 women) with mitral valve disease complicated with atrial fibrillation have been treated by PVOC since March 2000. During the mitral valve operations, all four pulmonary vein orifices were ablated using a ball-shaped cryo-probe. A newly designed cryo-probe was used for the last seven patients. Success was defined as atrial defibrillation within 6 months after the operation.
RESULTS
The success rate was 72.7% (16/22) of all patients, and improved from 66.6% to 85.7% (6/7) in the patients treated with the new cryo-probe. The mean left atrial dimension was smaller (50.2 +/- 4.1 vs. 61.5 +/- 9.4 mm, p < 0.01), and the duration of atrial fibrillation was also shorter (27.2 +/- 42.8 vs. 138.0 +/- 95.6 months, p < 0.01) in the successful group.
CONCLUSIONS
PVOC with mitral valve surgery is a simple and less invasive procedure, so could be an effective option for atrial fibrillation.
目的
评估二尖瓣手术期间肺静脉口冷冻消融术（PVOC）治疗心房颤动的有效性。
方法
自2000年3月以来，22例（12例男性和10例女性）二尖瓣疾病合并心房颤动患者接受了PVOC治疗。在二尖瓣手术期间，使用球形冷冻探头对所有四个肺静脉口进行消融。最后7例患者使用了新设计的冷冻探头。成功定义为术后6个月内心房除颤。
结果
所有患者的成功率为72.7%（16/22），使用新冷冻探头治疗的患者成功率从66.6%提高到85.7%（6/7）。成功组的平均左心房内径较小（50.2±4.1对61.5±9.4mm，p<0.01），心房颤动持续时间也较短（27.2±42.8对138.0±95.6个月，p<0.01）。
结论
二尖瓣手术联合PVOC是一种简单且侵入性较小的手术，因此可能是治疗心房颤动的有效选择。
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