Mofid Yassine, Ossant Frédéric, Imberdis Claude, Josse Gwendal, Patat Frédéric
Laboratoire UltraSons, Signaux et Instrumentation, Formation de Recherche en Evolution 2448, Centre National de la Recherche Scientifique, Tours, France.
IEEE Trans Ultrason Ferroelectr Freq Control. 2006 May;53(5):925-35. doi: 10.1109/tuffc.2006.1632683.
The aim of this study was to evaluate the potential of high-frequency static two-dimensional (2-D) elastography for in vivo exploration of the mechanical behavior of skin. Our device was based on the combination of a 20 MHz sonographer and a patented extensiometer device able to apply calibrated uniaxial stretching of the skin. We used a new algorithm to compute elastograms that improve elastographic signal-to-noise ratio (SNRe) without sacrificing resolution. Mechanical behavior was described according to the axial strain and lateral displacements induced in the tissue. The efficacy of the strain anpolyvinyl alcohol first evaluated in polyvinyl alcohol (PVA)-cryogel phantoms. Several in vivo experiments then were conducted, mainly with the multistretching averaging method, and demonstrated the potential of this technique in the evaluation of mechanical behavior of the dermis and the hypodermis under stress.
本研究的目的是评估高频静态二维（2-D）弹性成像技术在体内探测皮肤力学行为的潜力。我们的设备基于一台20 MHz超声诊断仪与一个能够对皮肤进行校准单轴拉伸的专利引伸计设备的组合。我们使用一种新算法来计算弹性图，该算法在不牺牲分辨率的情况下提高了弹性成像的信噪比（SNRe）。根据组织中产生的轴向应变和横向位移来描述力学行为。首先在聚乙烯醇（PVA）-冷冻凝胶体模中评估应变的效果。随后进行了多项体内实验，主要采用多拉伸平均法，证明了该技术在评估真皮和皮下组织在应力作用下力学行为方面的潜力。
