来自尼泊尔跨喜马拉雅地区的药用植物船盔乌头（Brühl）Stapf中的新黄酮苷。

New flavonoid glycosides from Aconitum naviculare (Brühl) Stapf, a medicinal herb from the trans-Himalayan region of Nepal.

作者信息

Shrestha Bharat Babu, Dall'Acqua Stefano, Gewali Mohan Bikram, Jha Pramod Kumar, Innocenti Gabbriella

机构信息

Central Department of Botany, Tribhuvan University, Kirtipur, Kathmandu, Nepal.

出版信息

Carbohydr Res. 2006 Sep 4;341(12):2161-5. doi: 10.1016/j.carres.2006.05.013. Epub 2006 Jun 9.

DOI:10.1016/j.carres.2006.05.013

PMID:16764845

Abstract

Three new flavonoid glycosides, 3-O-[beta-D-glucopyranosyl-(1-->3)-(4-O-trans-p-coumaroyl)-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranosyl]-7-O-[beta-D-glucopyranosyl-(1-->3)-alpha-L-rhamnopyranosyl]kaempferol, 3-O-[beta-D-glucopyranosyl-(1-->3)-(4-O-trans-p-coumaroyl)-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranosyl]-7-O-[beta-D-glucopyranosyl-(1-->3)-alpha-L-rhamnopyranosyl]quercetin and 7-O-[beta-D-glucopyranosyl-(1-->3)-alpha-L-rhamnopyranosyl]quercetin were isolated from the aqueous extract of the aerial parts of Aconitum naviculare. Their structures were elucidated by spectral analysis (HRAPI-TOF MS, 1H, 13C NMR, HMQC, HMBC, DFQ-COSY, ROESY and TOCSY).

摘要

从船形乌头地上部分的水提取物中分离出三种新的黄酮苷，即3-O-[β-D-吡喃葡萄糖基-(1→3)-(4-O-反式对香豆酰基)-α-L-鼠李吡喃糖基-(1→6)-β-D-吡喃葡萄糖基]-7-O-[β-D-吡喃葡萄糖基-(1→3)-α-L-鼠李吡喃糖基]山柰酚、3-O-[β-D-吡喃葡萄糖基-(1→3)-(4-O-反式对香豆酰基)-α-L-鼠李吡喃糖基-(1→6)-β-D-吡喃葡萄糖基]-7-O-[β-D-吡喃葡萄糖基-(1→3)-α-L-鼠李吡喃糖基]槲皮素和7-O-[β-D-吡喃葡萄糖基-(1→3)-α-L-鼠李吡喃糖基]槲皮素。通过光谱分析（高分辨大气压光电离飞行时间质谱、1H、13C核磁共振、异核多量子相干、异核多键相关、双量子滤波相关谱、旋转坐标系下核Overhauser效应谱和全相关谱）对它们的结构进行了阐明。