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腹腔镜输尿管松解术治疗输尿管子宫内膜异位症的疗效

Outcome of laparoscopic ureterolysis for ureteral endometriosis.

作者信息

Ghezzi Fabio, Cromi Antonella, Bergamini Valentino, Serati Maurizio, Sacco Alessandro, Mueller Michael D

机构信息

Department of Obstetrics and Gynecology, University of Insubria, Del Ponte Hospital, Varese, Italy.

出版信息

Fertil Steril. 2006 Aug;86(2):418-22. doi: 10.1016/j.fertnstert.2005.12.071. Epub 2006 Jun 9.

DOI:10.1016/j.fertnstert.2005.12.071
PMID:16764874
Abstract

OBJECTIVE

To evaluate the adequacy of laparoscopic ureterolysis as a primary treatment option for ureteral endometriosis.

DESIGN

Prospective collaborative cohort study.

SETTING

Gynecologic departments of three university hospitals.

PATIENT(S): Women with ureteral endometriosis exhibiting moderate-to-severe hydronephrosis on preoperative intravenous pyelography.

INTERVENTION(S): Laparoscopic ureterolysis.

MAIN OUTCOME MEASURE(S): Cure rate, disesase recurrence.

RESULT(S): Thirty-three patients underwent laparoscopic ureterolysis during the study period. Bilateral involvement of ureters was found in 4 (12.1%) cases. In women with unilateral lesions the left ureter was more frequently affected (24/29 vs. 5/29). Ureteral involvement was associated with uterosacral ligaments endometriosis in 65.5% (22/34) of cases. No inadvertent ureteral injuries occurred during ureterolysis. A partial wall resection of the ureter was necessary in one case and a segmental ureteral resection with vescicopsoas hitch was required in a women with intrinsic ureteral endometriosis. The median (range) follow-up time was 16 months (range: 3-53 months). Thirty-two patients (96.7%) had a patent ureter on the 3-month postoperative intravenous pyelography. The recurrence rate of ureteral lesions was 12.1% (4/33).

CONCLUSION(S): Our findings suggest that a conservative laparoscopic approach is an effective treatment option in most patients with ureteral endometriosis exhibiting moderate-to-severe hydronephrosis.

摘要

目的

评估腹腔镜输尿管松解术作为输尿管子宫内膜异位症主要治疗方法的充分性。

设计

前瞻性协作队列研究。

地点

三家大学医院的妇科。

患者

术前静脉肾盂造影显示有中度至重度肾积水的输尿管子宫内膜异位症女性。

干预措施

腹腔镜输尿管松解术。

主要观察指标

治愈率、疾病复发率。

结果

在研究期间,33例患者接受了腹腔镜输尿管松解术。4例(12.1%)患者双侧输尿管受累。单侧病变的女性中,左侧输尿管更常受累(24/29对5/29)。65.5%(22/34)的病例中输尿管受累与子宫骶骨韧带子宫内膜异位症有关。输尿管松解术中未发生意外输尿管损伤。1例患者需要进行输尿管部分壁切除术,1例患有原发性输尿管子宫内膜异位症的女性需要进行输尿管节段切除术并加行膀胱腰大肌固定术。中位(范围)随访时间为16个月(范围:3 - 53个月)。32例患者(96.7%)术后3个月静脉肾盂造影显示输尿管通畅。输尿管病变的复发率为12.1%(4/33)。

结论

我们的研究结果表明,对于大多数患有中度至重度肾积水的输尿管子宫内膜异位症患者,保守的腹腔镜手术方法是一种有效的治疗选择。

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