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以肾脏受累为主的坏死性血管炎

[Necrotizing vasculitis with predominant kidney involvement].

作者信息

Rodríguez Jornet A, Badal J M, Munne A, Marcos J M

机构信息

Sección de Nefrología, Hospital Sant Andreu, Manresa.

出版信息

Rev Clin Esp. 1991 Jan;188(1):28-33.

PMID:1676536
Abstract

We report five patients with necrotizing vasculitis with predominant renal involvement; the diagnostic and therapeutics was effected completely at regional hospital. We detach: a) the clinical presentation's forms with rapidly progressive renal failure with microscopic hematuria and minimal proteinuria; b) the biopsy of kidney with necrotizing vasculitis or necrotizing glomerulonephritis (microscopic polyarteritis). We review the necrotizing vasculitis with predominant renal involvement in its pathogenic, clinical and histological aspects, and we insist that the diagnostic and early treatment are fundamental for prognostic's improvement of these patients. We conclude that this diagnostic and treatment can be made in regional hospitals with sensible physicians by the theme.

摘要

我们报告了5例以肾脏受累为主的坏死性血管炎患者;诊断和治疗在地区医院全部完成。我们发现:a)临床表现为快速进展性肾衰竭,伴有镜下血尿和微量蛋白尿;b)肾脏活检显示为坏死性血管炎或坏死性肾小球肾炎(显微镜下多动脉炎)。我们从发病机制、临床和组织学方面回顾了以肾脏受累为主的坏死性血管炎,并且强调诊断和早期治疗对于改善这些患者的预后至关重要。我们得出结论,通过该主题,明智的医生在地区医院即可进行这种诊断和治疗。

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