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睑板双层旋转术后17年沙眼性倒睫复发

Recurrence of trachomatous trichiasis 17 years after bilamellar tarsal rotation procedure.

作者信息

Khandekar Rajiv, Al-Hadrami Khalfan, Sarvanan Natarajan, Al Harby Saleh, Mohammed Ali Jaffer

机构信息

Eye & Ear Health Care, Ministry of Health, Muscat, Oman.

出版信息

Am J Ophthalmol. 2006 Jun;141(6):1087-1091. doi: 10.1016/j.ajo.2006.01.024.

Abstract

PURPOSE

In 1989, World Health Organization consultant operated on trachomatous trichiasis (TT) cases in Dhakhiliya region of Oman. We evaluated their current ocular status.

DESIGN

This was an historic cohort study.

METHODS

This study was conducted in an in-house setting. Ninety-one patients with TT who underwent operation by the bilamellar tarsal rotation procedure (BTR) were our study population. Their preoperative, operative, and immediate postoperative data were retrieved from the register. Staff members located and visited these patients. They examined the eyes and determined their visual, TT, and corneal status. They interviewed participants with a close-ended questionnaire to assess the quality of life and satisfaction for the TT services that were offered.

RESULTS

Sixty-three patients could be followed. Among 72 eyes that had undergone operation 17 years earlier, the recurrence rate was 47.2% (95% CI, 35.7-58.8). In 21 unoperated eyes (55%), TT was noted. The association of TT recurrence to age, gender, type of TT, conjunctivitis, and active trachoma was tested. The BTR for minor trichiasis was the risk factor for recurrence of TT (adjusted odds ratio, 3.9; 95% CI, 1.4-10.8).

CONCLUSION

The high recurrence rate of TT, 17 years after BTR surgery and high rates of TT in eyes that did not undergo surgical procedure earlier suggest that the causes of high recurrence should be identified and addressed. The ongoing pathologic condition of scarring of upper lids of both operated and unoperated eyes could be responsible for lid status after 17 years of BTR surgeries. High percentage of refusals because of long-term high recurrence could pose a challenge to reach the "elimination of blinding trachoma" by 2020.

摘要

目的

1989年,世界卫生组织顾问在阿曼的达赫基利亚地区为沙眼性倒睫(TT)患者实施了手术。我们评估了他们目前的眼部状况。

设计

这是一项历史性队列研究。

方法

本研究在内部环境中进行。91例行双板层睑板旋转术(BTR)的TT患者为研究对象。从登记册中检索他们术前、术中及术后即刻的数据。工作人员找到并探访了这些患者。他们检查眼睛,确定其视力、TT及角膜状况。他们用封闭式问卷对参与者进行访谈,以评估所提供的TT服务的生活质量和满意度。

结果

63例患者可被随访。在17年前接受手术的72只眼中,复发率为47.2%(95%可信区间,35.7 - 58.8)。在未手术治疗的21只眼中(55%),发现了TT。对TT复发与年龄、性别、TT类型、结膜炎及活动性沙眼的相关性进行了检测。轻度倒睫的BTR是TT复发的危险因素(调整后的优势比,3.9;95%可信区间,1.4 - 10.8)。

结论

BTR手术后17年TT的高复发率以及早期未接受手术治疗的眼中TT的高发生率表明,应确定并解决高复发的原因。手术和未手术的上睑瘢痕形成的持续病理状况可能是BTR手术17年后眼睑状况的原因。由于长期高复发率导致的高拒绝率可能对到2020年实现“消除致盲性沙眼”构成挑战。

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