Arora Anju, Arora Sandeep
Department of Internal Medicine, Western Pennsylvania Hospital, Temple University Program, Pittsburgh, PA 15224, USA.
J Headache Pain. 2006 Sep;7(4):214-6. doi: 10.1007/s10194-006-0291-5. Epub 2006 Jun 15.
Triptans are specific agonists of the serotonergic 5-HT(1B/1D) receptors that have increasingly been used in the treatment of migraine and cluster headaches. Though they are generally considered safe, there have been a few reports of myocardial infarction and stroke associated with triptan use. We report a patient who developed spontaneous splenic infarction after the use of sumatriptan for the treatment of migraine headache.
曲坦类药物是血清素能5-HT(1B/1D)受体的特异性激动剂,越来越多地用于治疗偏头痛和丛集性头痛。尽管它们通常被认为是安全的,但已有一些关于使用曲坦类药物后发生心肌梗死和中风的报告。我们报告一名患者在使用舒马曲坦治疗偏头痛后发生自发性脾梗死。