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全挡板生物反应器的数值模拟:微分圆周平均混合平面法

Numerical simulation of a fully baffled biological reactor: the differential circumferential averaging mixing plane approach.

作者信息

Dubey Hitesh, Das Sarit Kumar, Panda Tapobrata

机构信息

Department of Mechanical Engineering, IIT Madras, Chennai 600036, India.

出版信息

Biotechnol Bioeng. 2006 Nov 5;95(4):754-66. doi: 10.1002/bit.21030.

DOI:10.1002/bit.21030
PMID:16767780
Abstract

A modified mixing plane approach for steady state simulation of flow field in fully baffled biological reactor is presented and discussed. Without requiring any experimental input, this approach of dividing the vessel into suitable number of connected and disconnected zones; solving steady state equation separately in each zone and then transferring information between them, provides a computationally less intensive alternative for simulating the flow in the whole vessel. Impeller used is the standard Rushton Turbine positioned at mid-height of the reactor and simulations are carried out using standard k-epsilon turbulence model implemented in CFD code FLUENT. Meshing is done using tetrahedral elements such that mesh size gradually increases from the center to the periphery. Most of the previous simulation works present only a few aspects of the flow field with scant importance to the energy balance in the tank and near tip turbulence. In this work, complete model prediction for velocity field and turbulence parameters (near tip and in the bulk region) are validated by comparison with experimental data. As compared to previous simulation works, the results predicted by this "Differential circumferential averaging mixing plane approach" show a better qualitative and quantitative agreement with the published experimental data. A distribution of energy dissipation in various zones of vessel is presented. Also a qualitative picture of flow field and stagnant zones inside the reactor is presented and discussed. Comparison of flow characteristics for different number of baffles shows that for the present dimension of the vessel, five baffles gives maximum enhanced mixing.

摘要

本文提出并讨论了一种用于全挡板生物反应器流场稳态模拟的改进混合平面方法。该方法无需任何实验输入,将容器划分为适当数量的连通和不连通区域;分别在每个区域求解稳态方程,然后在它们之间传递信息,为模拟整个容器内的流动提供了一种计算强度较低的替代方法。所使用的叶轮是位于反应器中部高度的标准 Rushton 涡轮,模拟使用 CFD 代码 FLUENT 中实现的标准 k-epsilon 湍流模型进行。使用四面体单元进行网格划分,使网格尺寸从中心到周边逐渐增大。以前的大多数模拟工作只展示了流场的几个方面,对罐内能量平衡和近叶尖湍流的重要性不大。在这项工作中,通过与实验数据比较,验证了对速度场和湍流参数(近叶尖和主体区域)的完整模型预测。与以前的模拟工作相比,这种“差分周向平均混合平面方法”预测的结果与已发表的实验数据在定性和定量上都有更好的一致性。给出了容器各区域的能量耗散分布。还给出并讨论了反应器内流场和停滞区域的定性图。不同挡板数量的流动特性比较表明,对于当前容器尺寸,五个挡板能实现最大程度的混合增强。

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