Montagnese A, Sturla M, Bruno I, Bracaglia R, Salgarello M, Seccia A, Farallo E
Division of Plastic Surgery, A. Gemelli General Hospital, Rome, Italy.
J Exp Clin Cancer Res. 2003 Dec;22(4 Suppl):219-22.
The Soft Tissue Sarcomas shows consisting mortality that grazes 50%. Commonly the histologic type, the largeness of the tumor and the degree of malignity, are considered prognostic factors influencing the survival of patients affected from such tumor. The aim of our study is to characterize the new prognostic factors influencing the local recidives and metastatic dissemination. We have analysed 17 possible clinical and histologic prognostic factors in 80 patients affected of soft tissue sarcomas. The results have dimonstrated that: the compartimentality and the cellular differentiation seem to be more influent to the insurgence of local recidives and metastasis; while the low malignity degree, the wide surgical margins and the histopatological characters of benignity can influense positively the survival.
软组织肉瘤的死亡率接近50%。通常，组织学类型、肿瘤大小和恶性程度被认为是影响此类肿瘤患者生存的预后因素。我们研究的目的是确定影响局部复发和转移扩散的新预后因素。我们分析了80例软组织肉瘤患者的17种可能的临床和组织学预后因素。结果表明：肿瘤的分区和细胞分化似乎对局部复发和转移的发生影响更大；而低恶性程度、广泛的手术切缘和良性的组织病理学特征可对生存产生积极影响。
