Bach Flemming W, Finnerup Nanna S B, Jensen Troels S
Aarhus Universitet, Dansk Smerteforskningscenter, og Arhus Universitetshospital, Arhus Sygehus, Neurologisk Afdeling.
Ugeskr Laeger. 2006 May 15;168(20):1964-6.
Neuropathic pain (NP) occurs secondary to lesions in the nervous system. The definition includes conditions with nervous system dysfunction, which creates problems with diagnostic classification. Lesions may be clinically identified, but signs of dysfunction are less specific. New knowledge of mechanisms behind NP has led to the suggestion that NP should be treated based on mechanisms rather than on diagnosis. However, it is not yet possible to identify mechanisms in individual patients, and present knowledge of drug effects builds on diagnosis. An algorithm for treatment of NP is presented.
神经性疼痛（NP）继发于神经系统损伤。该定义包括伴有神经系统功能障碍的情况，这给诊断分类带来了问题。损伤在临床上可能得以识别，但功能障碍的体征则不那么具有特异性。NP背后机制的新知识促使人们提出，NP应基于机制而非诊断进行治疗。然而，目前尚无法在个体患者中识别机制，且现有的药物作用知识是基于诊断建立的。本文提出了一种NP的治疗算法。
