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血清多巴胺-β-羟化酶活性与中枢和外周肾上腺素能神经元及肾上腺中多巴胺-β-羟化酶和酪氨酸羟化酶活性之间的相关性。

Correlation between serum dopamine-beta-hydroxylase activity and dopamine-beta-hydroxylase and tyrosine hydroxylase activities in central and peripheral adrenergic neurons and adrenal glands.

作者信息

Nagatsu T, Kato T, Numata Y, Ikuta K, Sano M, Nagatsu I, Takeuchi T, Matsuzaki M, Umezawa H

出版信息

Experientia. 1977 May 15;33(5):581-3. doi: 10.1007/BF01946508.

Abstract

Serum dopamine-beta-hydroxylase activity in spontaneously hypertensive rats and Wistar-Kyoto rats had a positive correlation with dopamine-beta-hydroxylase and tyrosine hydroxylase activities in mesenteric vessels, vas deferens, and adrenal glands at 14-16 weeks of age, a negative correlation with dopamine-beta-hydroxylase activity in locus coeruleus at 3 weeks and 14-16 weeks of age, and a positive correlation with tyrosine hydroxylase activity only at 3 weeks of age, but not at 14-16 weeks of age.

摘要

自发性高血压大鼠和Wistar-Kyoto大鼠的血清多巴胺-β-羟化酶活性在14至16周龄时与肠系膜血管、输精管和肾上腺中的多巴胺-β-羟化酶及酪氨酸羟化酶活性呈正相关,在3周龄以及14至16周龄时与蓝斑中的多巴胺-β-羟化酶活性呈负相关,仅在3周龄时与酪氨酸羟化酶活性呈正相关,而在14至16周龄时则无此相关性。

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