Meschia Michele, Pifarotti Paola, Bernasconi Francesco, Magatti Fabio, Viganò Riccardo, Bertozzi Rosanna, Barbacini Pietro
Department of Obstetrics and Gynecology, Ospedale G. Fornaroli, Magenta, Italy.
Am J Obstet Gynecol. 2006 Nov;195(5):1338-42. doi: 10.1016/j.ajog.2006.03.067. Epub 2006 Jun 12.
This study was undertaken to compare the efficacy and morbidity of 2 minimally invasive procedures for stress urinary incontinence.
This was a prospective randomized multicenter trial; 190 women with primary urodynamic stress incontinence were randomly assigned to tension-free vaginal tape (TVT) (n = 95) or intravaginal slingplasty (IVS) (n = 95). The primary and secondary outcome measures were rates of success and complications. SPSS software was used for data analysis.
At 2 years 92 and 87 patients were available in the TVT and IVS group for outcomes analysis. Subjectively, 80 (87%) and 68 (78%) women were cured, respectively. Objectively, a 1-hour pad test was negative in 78 (85%) and 63 (72%) patients. Eight of the patients assigned to IVS (9%) had vaginal erosion/infection, compared with none in the TVT group (P < .01).
Both procedures were effective for stress incontinence, but 9% of women treated with the IVS required removal of the tape for erosions.
本研究旨在比较两种治疗压力性尿失禁的微创手术的疗效和发病率。
这是一项前瞻性随机多中心试验；190例原发性尿动力学压力性尿失禁女性被随机分为无张力阴道吊带术（TVT）组（n = 95）或阴道内吊带成形术（IVS）组（n = 95）。主要和次要结局指标分别为成功率和并发症发生率。采用SPSS软件进行数据分析。
2年后，TVT组和IVS组分别有92例和87例患者可进行结局分析。主观上，分别有80例（87%）和68例（78%）女性治愈。客观上，78例（85%）和63例（72%）患者的1小时垫试验结果为阴性。IVS组有8例（9%）患者发生阴道糜烂/感染，而TVT组无1例发生（P <.01）。
两种手术治疗压力性尿失禁均有效，但接受IVS治疗的女性中有9%因糜烂需要取出吊带。
