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[1例肺癌化疗后多发性脓性肌炎病例]

[A case of multiple pyomyositis after chemotherapy for lung cancer].

作者信息

Yamada Kenji, Wasa Junji, Sugiura Hideshi, Horio Yoshitsugu

机构信息

Dept. of Orthopedic Surgery, Aichi Cancer Center Hospital.

出版信息

Gan To Kagaku Ryoho. 2006 Jun;33(6):837-40.

Abstract

We here describe a case of multiple pyomyositis in a 62-year-old man who had systemic chemotherapy for recurrent lung cancer. His initial symptoms consisted of fever and general fatigue, followed by progressive pain and swelling in his extremities, which mimicked deep venous thrombosis along with bacterial infection. He was admitted to the hospital for intravenous administration of antibiotics. MRI appeared very useful to find the intramuscular fluid collections with circumferential inflammatory changes, which confirmed diagnosis of the multiple pyomyositis. Surgical drainage as well as intravenous administration of antibiotics worked very well and improved clinical symptoms in a few weeks after the treatments. He could resume normal activities with minimum functional impairments in the extremities. Pyomyositis should be kept in mind as one of the adverse effects after chemotherapy for malignant tumors.

摘要

我们在此描述一例62岁男性的多发性脓性肌炎病例,该患者因复发性肺癌接受了全身化疗。他最初的症状包括发热和全身乏力,随后四肢逐渐出现疼痛和肿胀,类似于深部静脉血栓形成并伴有细菌感染。他因静脉注射抗生素而入院。MRI对于发现伴有周围炎症改变的肌内液体积聚非常有用,这证实了多发性脓性肌炎的诊断。手术引流以及静脉注射抗生素效果良好,治疗后几周内临床症状得到改善。他能够恢复正常活动,四肢功能仅有轻微受损。脓性肌炎应被视为恶性肿瘤化疗后的不良反应之一。

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