Ekser Burcin, Baldan Nicola, Margani Giuseppe, Furian Lucrezia, Frison Laura, Valente Marialuisa, Rigotti Paolo
Kidney and Pancreas Transplantation Unit, Department of Surgery and Organ Transplantation, University of Padova, Padova, Italy.
Transpl Int. 2006 Jun;19(6):485-91. doi: 10.1111/j.1432-2277.2006.00309.x.
Dual kidney transplantation (DKT) from marginal donors is increasingly used at many centers to help cope with the organ shortage problem. The disadvantages of DKT consist in longer operating times and the risk of surgical complications. DKT can be performed in two ways, i.e. using monolateral or bilateral procedures. From October 1999 to June 2005, 58 DKTs were performed at our unit. In 29 cases (group I), the kidneys were extraperitoneally placed bilaterally in the iliac fossae via two separate incisions; as of June 2003, monolateral kidney placement was preferred in 29 cases, whenever compatible with the recipient's morphological status (group II). After a mean follow-up of 51 +/- 19 months for group I and 15 +/- 7 months for group II, all patients are alive with 1-year graft survival rates of 93% and 96%, respectively. Mean operating times were 351 +/- 76 min in group I and 261 +/- 31 min in group II (P = 0.0001). The mean S-creatinine levels in groups I and II were 132 +/- 47 and 119 +/- 36 mumol/l, respectively, at 1 year. We observed eight surgical complications in group I and seven in group II. Both techniques proved safe, with no differences in surgical complication rates. The monolateral procedure has the advantage of a shorter operating time and the contralateral iliac fossa remains available for further retransplantation procedures.
许多中心越来越多地采用来自边缘供体的双肾移植(DKT)来应对器官短缺问题。DKT的缺点包括手术时间较长和手术并发症风险。DKT可以通过两种方式进行,即采用单侧或双侧手术。1999年10月至2005年6月,我们单位共进行了58例DKT。在29例(第一组)中,通过两个单独的切口将肾脏经腹膜外双侧置于髂窝;截至2003年6月,只要与受者的形态状况相符,29例中优先采用单侧肾脏放置(第二组)。第一组平均随访51±19个月,第二组平均随访15±7个月,所有患者均存活,1年移植肾存活率分别为93%和96%。第一组平均手术时间为351±76分钟,第二组为261±31分钟(P = 0.0001)。第一组和第二组1年时的平均血清肌酐水平分别为132±47和119±36μmol/L。我们在第一组观察到8例手术并发症,在第二组观察到7例。两种技术都证明是安全的,手术并发症发生率没有差异。单侧手术的优点是手术时间较短,对侧髂窝仍可用于进一步的再次移植手术。