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一体双侧单肾移植。

Two-as-one monolateral dual kidney transplantation.

机构信息

Department of Surgery, Transplantation and Advanced Technologies, Vascular Surgery and Organ Transplant Unit, University Hospital of Catania, Catania, Italy.

出版信息

Urology. 2011 Jan;77(1):227-30. doi: 10.1016/j.urology.2010.02.024.

Abstract

OBJECTIVES

Dual kidney transplantation (DKT) of marginal kidneys could offer transplant candidates a very satisfactory kidney transplantation in terms of renal function. However, DKT might be considered a major surgical procedure and, in older recipients, has a potentially greater risk of surgical complications compared with single kidney transplantation. Because of these findings, some transplant centers have replaced the classic bilateral placement of 2 kidneys with the monolateral placement of both kidneys.

METHODS

In a group of 35 DKTs performed during a 5-year period, we applied a new technique of monolateral placement of DKT in 10 recipients. In these 10 patients, the arteries and veins of the 2 kidneys were joined through a running suture, and the joined kidneys were anastomosed into the external iliac vessels in the recipient.

RESULTS

The delayed graft function rate was 20%. No surgical complications developed in the entire series. One patient experienced late rejection with ureteral stricture. The graft and patient survival rate at a median follow-up of 30 months was 90%.

CONCLUSIONS

To reduce the surgical risk and morbidity rate, the monolateral placement of both kidneys seems the safest method to perform DKT. The joined monolateral DKT, by reducing the cold ischemia time and the surgical trauma, could represent a step forward in the delicate treatment of these patients.

摘要

目的

边缘供肾的双肾移植(DKT)可在肾功能方面为移植受者提供非常满意的肾移植。然而,与单肾移植相比,DKT 可能被认为是一种主要的手术程序,并且在老年受者中,手术并发症的风险更高。由于这些发现,一些移植中心已经将经典的双侧 2 个肾脏放置改为单侧放置。

方法

在 5 年期间进行的 35 例 DKT 中,我们在 10 例受者中应用了 DKT 单侧放置的新技术。在这 10 例患者中,2 个肾脏的动静脉通过连续缝合连接,连接的肾脏吻合到受者的髂外血管。

结果

迟发性移植物功能障碍的发生率为 20%。整个系列均未发生手术并发症。1 例患者出现晚期排斥反应合并输尿管狭窄。中位随访 30 个月时,移植物和患者的存活率为 90%。

结论

为降低手术风险和发病率,双侧肾脏的单侧放置似乎是进行 DKT 的最安全方法。通过减少冷缺血时间和手术创伤,联合的单侧 DKT 可能代表了对这些患者进行精细化治疗的一个进步。

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