Habek Mario, Petravić Damir
University Department of Neurology, Zagreb School of Medicine and University Hospital Center, Zagreb, Croatia.
Clin Neuropharmacol. 2006 May-Jun;29(3):165-7. doi: 10.1097/01.WNF.0000220815.86478.5F.
Although cardiovascular side effects of sildenafil are recognized, little is known about stroke risk in patients who take this drug. We report a patient with multiple strokes in the posterior cerebral circulation in close temporal association with sildenafil use. This case report further emphasize that stroke is, although rare, real side effect of sildenafil. Potential users should be warned before taking it, especially if they have other stroke risk factors, as recommended by the manufacturer.
尽管西地那非的心血管副作用已为人所知,但对于服用该药患者的中风风险却知之甚少。我们报告了一名患者,其大脑后循环出现多次中风,且与使用西地那非在时间上密切相关。本病例报告进一步强调,中风虽是西地那非罕见的副作用,但确实存在。应如制造商所建议的那样,在潜在使用者服用该药前对其进行警告,尤其是那些有其他中风风险因素的人。