Division of Hemato-Oncology, Department of Internal Medicine, Seoul Paik Hospital, 04551 Seoul, Republic of Korea.
Inje University, College of Medicine, 47392 Busan, Republic of Korea.
Rev Cardiovasc Med. 2021 Mar 30;22(1):185-189. doi: 10.31083/j.rcm.2021.01.286.
Sildenafil citrate and its generic forms are widely used to treat erectile dysfunction worldwide. Sildenafil citrate associated myocardial infarction is rarely reported in patients with no previous coronary artery disease. Herein, we present a case of a 40-year-old man with no cardiovascular risk factors other than heavy smoking and heavy drinking with no known previous ischemic symptoms, who had an ST-segment elevation myocardial infarction after receiving sildenafil citrate. From this case report, we emphasize that as sildenafil is increasingly being used as a recreational drug as it is widely available without a physician's prescription, physicians should be aware that it may reveal the underlying cardiovascular problem. Thus, physicians must also consider the underlying medical conditions when prescribing sildenafil.
枸橼酸西地那非及其仿制药被广泛用于治疗全球范围内的勃起功能障碍。在没有先前冠状动脉疾病的患者中,枸橼酸西地那非相关的心肌梗死很少见。在此,我们报告一例 40 岁男性,除了大量吸烟和酗酒外,没有其他心血管危险因素,也没有已知的缺血症状,在服用枸橼酸西地那非后发生 ST 段抬高型心肌梗死。从这个病例报告中,我们强调,由于枸橼酸西地那非作为一种娱乐性药物越来越多地被使用,因为它可以在没有医生处方的情况下广泛获得,医生应该意识到它可能会揭示潜在的心血管问题。因此,医生在开具枸橼酸西地那非时也必须考虑潜在的医疗状况。