Lee Vincent, Cheng Pik Shun, Chik Ki Wai, Wong Gary W K, Shing Matthew M K, Li Chi Kong
Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong.
J Pediatr Hematol Oncol. 2006 May;28(5):293-5. doi: 10.1097/01.mph.0000212907.14642.41.
We describe two pediatric patients who developed autoimmune hypothyroidism 2 years after unrelated allogeneic hematopoietic stem cell transplantation. The causes of post-transplantation autoimmune hypothyroidism are probably multiple. In these two patients, the presence of chronic graft-versus-host disease may be the most significant contributing factor.
我们描述了两名儿科患者,他们在接受非亲缘异基因造血干细胞移植两年后患上了自身免疫性甲状腺功能减退症。移植后自身免疫性甲状腺功能减退症的病因可能是多方面的。在这两名患者中,慢性移植物抗宿主病的存在可能是最重要的促成因素。