Hossain H, Chakraborty T
Institut für Medizinische Mikrobiologie, Frankfurter Strasse 107, 35392 , Giessen.
Internist (Berl). 2006 Jun;47 Suppl 1:S6, S8-13. doi: 10.1007/s00108-006-1627-6.
The complex interaction between a pathogen and a host is the molecular basis of infectious diseases. Microarray technology is a powerful tool to investigate the crosstalk between pathogen and the host as it assesses whole genome expression profiles in response to disease. Deciphering the molecular details on both sides of the host-pathogen interaction will increase our understanding of the pathogenesis of infectious diseases and offer improvements in their diagnosis, treatment, prognosis, and prevention.
病原体与宿主之间的复杂相互作用是传染病的分子基础。微阵列技术是研究病原体与宿主之间相互作用的有力工具,因为它可以评估针对疾病的全基因组表达谱。解读宿主 - 病原体相互作用双方的分子细节将增进我们对传染病发病机制的理解,并在其诊断、治疗、预后和预防方面带来改善。