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How should complex perianal Crohn's disease be treated in the Remicade era.

作者信息

Poritz Lisa S

机构信息

Department of Surgery, The Milton S. Hershey Medical Center, Pennsylvania State University, PA 17033, USA.

出版信息

J Gastrointest Surg. 2006 May;10(5):633-4. doi: 10.1007/BF03239968.

DOI:10.1007/BF03239968
PMID:16773757
Abstract
摘要

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How should complex perianal Crohn's disease be treated in the Remicade era.在类克时代，复杂肛周克罗恩病应如何治疗？
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Autologous fibroblasts transplant after infliximab administration: a new approach in Crohn's perianal fistulas? Brief clinical report.英夫利昔单抗给药后自体成纤维细胞移植：克罗恩病肛周瘘管的一种新方法？简要临床报告。
Int J Colorectal Dis. 2007 Sep;22(9):1135-6. doi: 10.1007/s00384-006-0141-6. Epub 2006 May 30.
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Combined seton placement, infliximab infusion, and maintenance immunosuppressives improve healing rate in fistulizing anorectal Crohn's disease: a single center experience.联合挂线疗法、英夫利昔单抗输注及维持性免疫抑制剂可提高肛瘘型克罗恩病的愈合率：单中心经验
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Treatment of perianal fistulas in Crohn's disease by local injection of antibody to TNF-alpha accounts for a favourable clinical response in selected cases: a pilot study.通过局部注射抗TNF-α抗体治疗克罗恩病肛周瘘管在部分病例中取得了良好的临床疗效：一项初步研究。
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本文引用的文献

1
Infliximab maintenance therapy for fistulizing Crohn's disease.英夫利昔单抗用于瘘管性克罗恩病的维持治疗。
N Engl J Med. 2004 Feb 26;350(9):876-85. doi: 10.1056/NEJMoa030815.
2
Combined seton placement, infliximab infusion, and maintenance immunosuppressives improve healing rate in fistulizing anorectal Crohn's disease: a single center experience.联合挂线疗法、英夫利昔单抗输注及维持性免疫抑制剂可提高肛瘘型克罗恩病的愈合率：单中心经验
Dis Colon Rectum. 2003 May;46(5):577-83. doi: 10.1007/s10350-004-6611-4.
3
Remicade does not abolish the need for surgery in fistulizing Crohn's disease.
类克并不能消除瘘管性克罗恩病患者对手术的需求。
Dis Colon Rectum. 2002 Jun;45(6):771-5. doi: 10.1007/s10350-004-6296-8.
4
Diagnosis and treatment of perianal fistulas in Crohn disease.克罗恩病肛周瘘管的诊断与治疗
Ann Intern Med. 2001 Nov 20;135(10):906-18. doi: 10.7326/0003-4819-135-10-200111200-00011.
5
Infliximab for the treatment of fistulas in patients with Crohn's disease.英夫利昔单抗用于治疗克罗恩病患者的瘘管。
N Engl J Med. 1999 May 6;340(18):1398-405. doi: 10.1056/NEJM199905063401804.