Jackson Anne, Heukelbach Jörg, Calheiros Cláudia Maria Lins, Soares Valquíria de Lima, Harms Gundel, Feldmeier Hermann
Department of Medical Microbiology and Immunology of Infection, Institute for Infection Medicine, Berlin, 12203, Germany.
Clin Infect Dis. 2006 Jul 15;43(2):e13-8. doi: 10.1086/505221. Epub 2006 Jun 8.
Cutaneous larva migrans (CLM) is a common but neglected parasitic skin disease in impoverished communities of the developing world.
To describe the clinical features and the morbidity associated with CLM, active-case finding was performed during rainy and dry seasons in a rural community in the state of Alagoas, Northeast Brazil.
A total of 62 individuals received a diagnosis for CLM, and among them there were a total of 75 larval tracks. The number of tracks per person ranged from 1 to 3. Children <9 years old were affected significantly more often than other age groups (P<.001). Children had their lesions mainly on the buttocks, genitals, and hands, whereas in older patients, the majority of lesions were located on the feet. Twenty-four percent of the 75 lesions were superinfected. Bacterial superinfection was more common among children. All but 1 patient complained about itching, and 84% of the 62 patients complained about sleep disturbances. Itching was classified as being severe by 61% of patients. Approximately 40% of the 62 patients had attempted to treat their creeping eruption previously. Larvae moved forward 2.7 mm per day. There was a significant correlation between the length of the track and the duration of infestation ( rho =.53; P<.0001).
CLM is a common parasitic skin disease in this rural community, with different topographic patterns of lesions in children and adults. CLM is associated with considerable morbidity. The length of the track can be used to estimate the duration of infestation.
皮肤幼虫移行症（CLM）是发展中国家贫困社区一种常见但被忽视的寄生虫性皮肤病。
为描述CLM的临床特征及与之相关的发病率，在巴西东北部阿拉戈斯州的一个农村社区，于雨季和旱季开展了主动病例发现工作。
共有62人被诊断为CLM，他们身上共有75条幼虫移行痕迹。每人的痕迹数量在1至3条之间。9岁以下儿童比其他年龄组受影响的频率显著更高（P<0.001）。儿童的皮损主要位于臀部、生殖器和手部，而在老年患者中，大多数皮损位于足部。75处皮损中有24%发生了继发感染。细菌继发感染在儿童中更为常见。62名患者中除1人外均抱怨有瘙痒，62名患者中有84%抱怨有睡眠障碍。61%的患者将瘙痒归类为严重。62名患者中约40%此前曾试图自行治疗匐行疹。幼虫每天向前移动2.7毫米。移行痕迹的长度与感染持续时间之间存在显著相关性（rho = 0.53；P<0.0001）。
CLM是这个农村社区一种常见的寄生虫性皮肤病，儿童和成人的皮损部位模式不同。CLM与相当高的发病率相关。移行痕迹的长度可用于估计感染持续时间。
