Vearrier David, Buka Robert L, Roberts Brandie, Cunningham Bari B, Eichenfield Lawrence F, Friedlander Sheila F
Childrens' Hospital and Health Center, University of California, San Diego, California 92123, USA.
Pediatr Dermatol. 2006 May-Jun;23(3):219-24. doi: 10.1111/j.1525-1470.2006.00221.x.
Elastosis perforans serpiginosa is a rare chronic dermatosis characterized by extrusion of altered elastic fibers through the epidermis. It often occurs in association with a variety of connective tissue disorders, and may develop following penicillamine therapy; however, it may also present without comorbidities. There are currently no well-established protocols for the investigation of possible associated disorders in patients who present with elastosis perforans serpiginosa. We describe three patients with idiopathic elastosis perforans serpiginosa seen at our clinic and review the standard of care among 31 pediatric dermatologists surveyed who have cared for such a patient within the last 2 years. Based upon the results of our survey, we conclude that most pediatric dermatologists limit their evaluation of such patients to a thorough patient history and physical examination. This limited approach may be a sufficient evaluation in affected patients who are otherwise healthy.
匐行性穿通性弹力纤维病是一种罕见的慢性皮肤病，其特征是变性的弹性纤维穿过表皮。它常与多种结缔组织疾病相关，可能在青霉胺治疗后发生；然而，它也可能在没有合并症的情况下出现。目前，对于匐行性穿通性弹力纤维病患者可能存在的相关疾病，尚无成熟的调查方案。我们描述了在我们诊所就诊的3例特发性匐行性穿通性弹力纤维病患者，并回顾了31位在过去2年内诊治过此类患者的儿科皮肤科医生的治疗标准。基于我们的调查结果，我们得出结论，大多数儿科皮肤科医生对这类患者的评估仅限于全面的病史询问和体格检查。对于其他方面健康的受影响患者，这种有限的评估方法可能就足够了。
