Di Lernia Vito, Ricci Cinzia
Operative Unit of Dermatology, 1st Medical Department, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy.
Pediatr Dermatol. 2006 May-Jun;23(3):255-8. doi: 10.1111/j.1525-1470.2006.00229.x.
Folliculitis spinulosa decalvans is an uncommon condition characterized by follicular hyperkeratosis, followed by scarring alopecia. We report a 12-year-old boy affected by keratotic papules of the scalp and keratosis pilaris of the limbs who developed erythema, pustules, and scale crusts on the scalp associated with scarring alopecia. Histologic examination showed follicular and interfollicular hyperkeratosis, follicular plugging, mild inflammation, and focal scarring. A transient remission of the inflammatory changes on the scalp was obtained after treatment with isotretinoin. The follicular spinulous hyperkeratosis persisted. A severe relapse of the scalp inflammation was observed during a 2-year follow-up.
脱发性棘状毛囊角化病是一种罕见的疾病，其特征为毛囊角化过度，继以瘢痕性脱发。我们报告一名12岁男孩，头皮有角化性丘疹，四肢有毛发角化病，头皮出现红斑、脓疱和鳞屑痂，并伴有瘢痕性脱发。组织学检查显示毛囊和毛囊间角化过度、毛囊堵塞、轻度炎症和局灶性瘢痕形成。异维A酸治疗后，头皮炎症变化出现短暂缓解。毛囊棘状角化过度持续存在。在2年的随访期间，观察到头皮炎症严重复发。
