患有哈丁普病的儿童出现类似肠病性肢端皮炎的皮疹。

Acrodermatitis enteropathica-like eruptions in a child with Hartnup disease.

作者信息

Seyhan Muammer Eşrefoğlu, Selimoğlu Mukadder Ayşe, Ertekin Vildan, Fidanoğlu Osman, Altinkaynak Sevin

机构信息

Department of Dermatology, Inönü University, Malatya, Faculty of Medicine, Atatürk University, Erzurum, Turkey.

出版信息

Pediatr Dermatol. 2006 May-Jun;23(3):262-5. doi: 10.1111/j.1525-1470.2006.00231.x.

DOI:10.1111/j.1525-1470.2006.00231.x

PMID:16780476

Abstract

Acrodermatitis enteropathica-like eruptions, not related to zinc deficiency, have been rarely reported in some metabolic disorders. Reported patients usually had low levels of essential amino acids, particularly isoleucine. Here we report a girl who first presented with an acrodermatitis enteropathica-like eruption and eventually had the diagnosis of Hartnup disease with a normal isoleucine level. We discuss the probable cause of her skin lesions and the differential diagnosis with pellagra.

摘要

在一些代谢紊乱疾病中，曾有罕见报道出现与锌缺乏无关的肠病性肢端皮炎样皮疹。报告的患者通常必需氨基酸水平较低，尤其是异亮氨酸。在此，我们报告一名女孩，她最初表现为肠病性肢端皮炎样皮疹，最终被诊断为哈氏病，而异亮氨酸水平正常。我们讨论了她皮肤病变的可能原因以及与糙皮病的鉴别诊断。