Kasner Scott E
Comprehensive Stroke Center, Department of Neurology, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA.
Lancet Neurol. 2006 Jul;5(7):603-12. doi: 10.1016/S1474-4422(06)70495-1.
No single outcome measure can describe or predict all dimensions of recovery and disability after acute stroke. Several scales have proven reliability and validity in stroke trials, including the National Institutes of Health stroke scale (NIHSS), the modified Rankin scale (mRS), the Barthel index (BI), the Glasgow outcome scale (GOS), and the stroke impact scale (SIS). Several scales have been combined in stroke trials to derive a global statistic to better define the effect of acute interventions, although this composite statistic is not clinically tenable. In practice, the NIHSS is useful for early prognostication and serial assessment, whereas the BI is useful for planning rehabilitative strategies. The mRS and GOS provide summary measures of outcome and might be most relevant to clinicians and patients considering early intervention. The SIS was designed to measure the patient's perspective on the effect of stroke. Familiarity with these scales could improve clinicians' interpretation of stroke research and their clinical decision-making.
没有单一的结果指标能够描述或预测急性中风后恢复和残疾的所有方面。在中风试验中，有几种量表已被证明具有可靠性和有效性，包括美国国立卫生研究院卒中量表（NIHSS）、改良Rankin量表（mRS）、巴氏指数（BI）、格拉斯哥预后量表（GOS）和卒中影响量表（SIS）。在中风试验中，几种量表已被组合起来以得出一个综合统计量，以便更好地确定急性干预的效果，尽管这个综合统计量在临床上并不适用。在实践中，NIHSS有助于早期预后评估和系列评估，而BI有助于制定康复策略。mRS和GOS提供了结果的综合测量，对于考虑早期干预的临床医生和患者可能最为相关。SIS旨在衡量患者对中风影响的看法。熟悉这些量表可以提高临床医生对中风研究的解读能力及其临床决策能力。
