Sanderson Helen S, Clarke Paul R
Biomedical Research Centre, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, Scotland, UK.
Curr Biol. 2006 Jun 20;16(12):R466-8. doi: 10.1016/j.cub.2006.05.032.
The small GTPase Ran has been shown to regulate HURP, a protein that interacts with several mitotic spindle assembly factors. This discovery sheds new light on the role of Ran in the fidelity of mitosis and in cancer.
小GTP酶Ran已被证明可调节HURP，HURP是一种与多种有丝分裂纺锤体组装因子相互作用的蛋白质。这一发现为Ran在有丝分裂保真度及癌症中的作用提供了新的线索。
