Pikas O B
Lik Sprava. 2000 Oct-Dec(7-8):30-3.
Results are highlighted of the study into the pulmonary surfactant in healthy subjects. as well as in those afflicted with pulmonary tuberculosis who abused alcoholic drinks, with the aid of the chromotography techniques. It has been ascertained that activity of the pulmonary surfactant is dependent upon the clinical form of tuberculosis, its extension and presence of alcoholism. The lipid polyunsaturated fatty acids, with the linoleic (C18:2) and arachidonic (C20:4) acids being the most sensitive ones to the process of lipid peroxidation (LPO), and the study into the spectrum of lipid fatty acids in the expired air consensate suggest intencity of LPO in the pulmonary surfactant and permit carrying out its correction in a timely fashion during the process of treatment.
研究结果突出了在健康受试者以及患有肺结核且酗酒者中借助色谱技术对肺表面活性物质的研究。已确定肺表面活性物质的活性取决于肺结核的临床类型、其范围以及酗酒情况。脂质多不饱和脂肪酸中，亚油酸（C18:2）和花生四烯酸（C20:4）对脂质过氧化（LPO）过程最为敏感，对呼出气体冷凝物中脂质脂肪酸谱的研究表明肺表面活性物质中LPO的强度，并允许在治疗过程中及时进行纠正。
