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通过胎粪分析确定药物滥用的患病率。

Determination of the prevalence of drug misuse by meconium analysis.

作者信息

Williamson S, Jackson L, Skeoch C, Azzim G, Anderson R

机构信息

Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, UK.

出版信息

Arch Dis Child Fetal Neonatal Ed. 2006 Jul;91(4):F291-2. doi: 10.1136/adc.2005.078642.

DOI:10.1136/adc.2005.078642
PMID:16790733
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2672735/
Abstract

In a pilot study to determine the local prevalence of maternal drug misuse, meconium from 400 infants was analysed for metabolites of eight controlled drugs. Cannabinoids were found in 13.25%, cocaine in 2.75%, and amphetamine in 1.75%. The prevalence of opiate and benzodiazepine misuse was masked by the presence of prescribed drugs so was undeterminable.

摘要

在一项确定当地产妇药物滥用情况的试点研究中,对400名婴儿的胎粪进行了分析,以检测8种管制药物的代谢物。发现13.25%的胎粪中含有大麻素,2.75%含有可卡因,1.75%含有苯丙胺。由于处方药的存在,阿片类药物和苯二氮卓类药物滥用的流行情况被掩盖,因此无法确定。

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本文引用的文献

1
Comparison of meconium and neonatal hair analysis for detection of gestational exposure to drugs of abuse.胎粪与新生儿毛发分析在检测孕期药物滥用暴露方面的比较。
Arch Dis Child Fetal Neonatal Ed. 2003 Mar;88(2):F98-F100. doi: 10.1136/fn.88.2.f98.
2
Estimates of illicit drug use during pregnancy by maternal interview, hair analysis, and meconium analysis.通过产妇访谈、毛发分析和胎粪分析对孕期非法药物使用情况的估计。
J Pediatr. 2001 Mar;138(3):344-8. doi: 10.1067/mpd.2001.111429.
3
The Maternal Lifestyle Study: drug use by meconium toxicology and maternal self-report.孕产妇生活方式研究:通过胎粪毒理学和孕产妇自我报告来了解药物使用情况
Pediatrics. 2001 Feb;107(2):309-17. doi: 10.1542/peds.107.2.309.
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Drug screening of meconium in infants of drug-dependent mothers: an alternative to urine testing.
J Pediatr. 1989 Sep;115(3):474-7. doi: 10.1016/s0022-3476(89)80860-1.
5
Drug screening of newborns by meconium analysis: a large-scale, prospective, epidemiologic study.通过胎粪分析对新生儿进行药物筛查:一项大规模、前瞻性的流行病学研究。
Pediatrics. 1992 Jan;89(1):107-13.