通过胎粪分析确定药物滥用的患病率。
Determination of the prevalence of drug misuse by meconium analysis.
作者信息
Williamson S, Jackson L, Skeoch C, Azzim G, Anderson R
机构信息
Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, UK.
出版信息
Arch Dis Child Fetal Neonatal Ed. 2006 Jul;91(4):F291-2. doi: 10.1136/adc.2005.078642.
Abstract
In a pilot study to determine the local prevalence of maternal drug misuse, meconium from 400 infants was analysed for metabolites of eight controlled drugs. Cannabinoids were found in 13.25%, cocaine in 2.75%, and amphetamine in 1.75%. The prevalence of opiate and benzodiazepine misuse was masked by the presence of prescribed drugs so was undeterminable.
摘要
在一项确定当地产妇药物滥用情况的试点研究中，对400名婴儿的胎粪进行了分析，以检测8种管制药物的代谢物。发现13.25%的胎粪中含有大麻素，2.75%含有可卡因，1.75%含有苯丙胺。由于处方药的存在，阿片类药物和苯二氮卓类药物滥用的流行情况被掩盖，因此无法确定。
相似文献
1
Determination of the prevalence of drug misuse by meconium analysis.
Arch Dis Child Fetal Neonatal Ed. 2006 Jul;91(4):F291-2. doi: 10.1136/adc.2005.078642.
2
Multiple birth concordance of street drug assays of meconium analysis.
Vet Hum Toxicol. 1995 Aug;37(4):318-9.
3
Prevalence of gestational exposure to cannabis in a Mediterranean city by meconium analysis.
Acta Paediatr. 2007 Dec;96(12):1734-7. doi: 10.1111/j.1651-2227.2007.00535.x. Epub 2007 Oct 22.
4
A comparison of meconium, maternal urine and neonatal urine for detection of maternal drug use during pregnancy.
J Forensic Sci. 1994 Jan;39(1):150-8.
5
Estimates of illicit drug use during pregnancy by maternal interview, hair analysis, and meconium analysis.
J Pediatr. 2001 Mar;138(3):344-8. doi: 10.1067/mpd.2001.111429.
6
Drug screening of newborns by meconium analysis: a large-scale, prospective, epidemiologic study.
Pediatrics. 1992 Jan;89(1):107-13.
7
Drug screening in newborns and mothers using meconium samples, paired urine samples, and interviews.
J Perinatol. 1995 May-Jun;15(3):199-202.
8
The Maternal Lifestyle Study: drug use by meconium toxicology and maternal self-report.
Pediatrics. 2001 Feb;107(2):309-17. doi: 10.1542/peds.107.2.309.
9
Testing for fetal exposure to illicit drugs using umbilical cord tissue vs meconium.
J Perinatol. 2006 Jan 1;26(1):11-4. doi: 10.1038/sj.jp.7211416.
10
Novel methods for the detection of drug and alcohol exposure during pregnancy: implications for maternal and child health.
Clin Pharmacol Ther. 2008 Apr;83(4):631-4. doi: 10.1038/sj.clpt.6100506. Epub 2008 Feb 20.
引用本文的文献
1
Illicit drug use in late pregnancy associated with stillbirth and eclampsia.
Obstet Med. 2010 Sep;3(3):113-4. doi: 10.1258/om.2010.090061. Epub 2010 Sep 17.
2
Illicit substance use in pregnancy - a review.
Obstet Med. 2010 Sep;3(3):94-100. doi: 10.1258/om.2010.100014. Epub 2010 Sep 17.
3
Reducing low birth weight: prioritizing action to address modifiable risk factors.
J Public Health (Oxf). 2017 Mar 1;39(1):122-131. doi: 10.1093/pubmed/fdv212.
4
Substance abuse among antenatal patients at jos university teaching hospital, north central Nigeria.
J West Afr Coll Surg. 2012 Apr;2(2):50-62.
5
Cannabis and psychosis: Neurobiology.
Indian J Psychiatry. 2014 Jan;56(1):8-16. doi: 10.4103/0019-5545.124708.
6
Cocaine use during pregnancy assessed by hair analysis in a Canary Islands cohort.
BMC Pregnancy Childbirth. 2012 Jan 9;12:2. doi: 10.1186/1471-2393-12-2.
7
Molecular mechanisms of maternal cannabis and cigarette use on human neurodevelopment.
Eur J Neurosci. 2011 Nov;34(10):1574-83. doi: 10.1111/j.1460-9568.2011.07884.x.
8
Neurobiological consequences of maternal cannabis on human fetal development and its neuropsychiatric outcome.
Eur Arch Psychiatry Clin Neurosci. 2009 Oct;259(7):395-412. doi: 10.1007/s00406-009-0027-z. Epub 2009 Jul 2.
本文引用的文献
1
Comparison of meconium and neonatal hair analysis for detection of gestational exposure to drugs of abuse.
Arch Dis Child Fetal Neonatal Ed. 2003 Mar;88(2):F98-F100. doi: 10.1136/fn.88.2.f98.
2
Estimates of illicit drug use during pregnancy by maternal interview, hair analysis, and meconium analysis.
J Pediatr. 2001 Mar;138(3):344-8. doi: 10.1067/mpd.2001.111429.
3
The Maternal Lifestyle Study: drug use by meconium toxicology and maternal self-report.
Pediatrics. 2001 Feb;107(2):309-17. doi: 10.1542/peds.107.2.309.
4
Drug screening of meconium in infants of drug-dependent mothers: an alternative to urine testing.
J Pediatr. 1989 Sep;115(3):474-7. doi: 10.1016/s0022-3476(89)80860-1.
5
Drug screening of newborns by meconium analysis: a large-scale, prospective, epidemiologic study.
Pediatrics. 1992 Jan;89(1):107-13.
Zotero 插件