Yoon So Hee, Moon Jeong Hee, Choi Kyung Mi, Kim Myung Soo
National Creative Research Initiative Center for Control of Reaction Dynamics and School of Chemistry, Seoul National University, Seoul 151-742, Korea.
Rapid Commun Mass Spectrom. 2006;20(14):2201-8. doi: 10.1002/rcm.2584.
A deflection system consisting of four deflectors was designed and used to reduce the interference from post-source decay (PSD) product ions in photodissociation (PD) tandem time-of-flight (TOF) mass spectrometry. For simple protonated peptides generated by matrix-assisted laser desorption/ionization, the presence of PSD product ions at the laser irradiation spot was found to noticeably alter the minor peaks in the PD spectra even though the major ones were hardly affected. Other benefits from the use of the deflection system such as the improvement in the resolving power in PSD tandem mass spectra are discussed.
设计了一种由四个偏转器组成的偏转系统，并将其用于减少光解离（PD）串联飞行时间（TOF）质谱中源后衰变（PSD）产物离子的干扰。对于通过基质辅助激光解吸/电离产生的简单质子化肽，发现激光照射点处PSD产物离子的存在会显著改变PD谱中的小峰，尽管主峰几乎不受影响。还讨论了使用该偏转系统的其他益处，例如PSD串联质谱中分辨率的提高。
