Xue F S, Li C W, Sun H T, Liu K P, Zhang G H, Xu Y C, Liu Y, Yu L
Department of Anaesthesiology, Plastic Surgery Hospital. Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
Anaesthesia. 2006 Jul;61(7):639-45. doi: 10.1111/j.1365-2044.2006.04685.x.
The circulatory responses to fibreoptic intubation under general anaesthesia were studied in 60 adult female patients who were randomly assigned to receive either the oral or nasal route for insertion. Non-invasive blood pressure and heart rate were recorded before anaesthesia induction (baseline values), immediately after anaesthesia induction (post-induction values), at intubation and every minute for a further 5 min. The product of heart rate and systolic blood pressure (rate pressure product) at every time point was also calculated. The results showed that both fibreoptic orotracheal intubation and fibreoptic nasotracheal intubation resulted in significant increases in blood pressure, heart rate and rate pressure product compared to baseline and post-induction values. The times required to reach the maximum values of systolic blood pressure and heart rate were significantly longer in the fibreoptic nasotracheal intubation group than in the fibreoptic orotracheal intubation group. There were no significant differences between the two groups in blood pressure, heart rate and rate pressure product at any measuring point, or in the maximum values during observation. The time required for recovery of systolic blood pressure to the post-induction value was not significantly different between the two groups, but the time required for recovery of heart rate to post-induction value was significantly longer in the fibreoptic orotracheal intubation group than in the fibreoptic nasotracheal intubation group. It was concluded that both fibreoptic orotracheal and fibreoptic nasotracheal intubations could cause a similar magnitude of circulatory responses in general anaesthetised, female adults, but the tachycardic response to fibreoptic orotracheal intubation lasted longer than that to fibreoptic nasotracheal intubation.
在60例成年女性患者中研究了全身麻醉下纤维支气管镜插管的循环反应,这些患者被随机分配接受经口或经鼻插入途径。在麻醉诱导前(基线值)、麻醉诱导后即刻(诱导后值)、插管时以及随后5分钟内每分钟记录无创血压和心率。还计算了每个时间点的心率与收缩压乘积(率压乘积)。结果显示,与基线值和诱导后值相比,纤维支气管镜经口气管插管和纤维支气管镜经鼻气管插管均导致血压、心率和率压乘积显著升高。纤维支气管镜经鼻气管插管组达到收缩压和心率最大值所需的时间明显长于纤维支气管镜经口气管插管组。两组在任何测量点的血压、心率和率压乘积或观察期间的最大值均无显著差异。两组收缩压恢复到诱导后值所需的时间无显著差异,但纤维支气管镜经口气管插管组心率恢复到诱导后值所需的时间明显长于纤维支气管镜经鼻气管插管组。结论是,在全身麻醉的成年女性中,纤维支气管镜经口气管插管和纤维支气管镜经鼻气管插管均可引起相似程度的循环反应,但纤维支气管镜经口气管插管引起的心动过速反应持续时间长于纤维支气管镜经鼻气管插管。