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经喉罩气道行气管插管时血流动力学反应的对比研究

Comparative study of hemodynamic responses to orotracheal intubation with intubating laryngeal mask airway.

作者信息

Zhang Guo-hua, Xue Fu-shan, Sun Hai-yan, Li Cheng-wen, Sun Hai-tao, Li Ping, Liu Kun-peng

机构信息

Department of Anesthesiology, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100041, China.

出版信息

Chin Med J (Engl). 2006 Jun 5;119(11):899-904.

Abstract

BACKGROUND

Intubating laryngeal mask airway (ILMA) offers a new approach for orotracheal intubation and is expected to produce less cardiovascular stress responses. However, the available studies provide inconsistent results. The purpose of this study was to identify whether there is a clinically relevant difference in hemodynamic responses to orotracheal intubation by using ILMA and direct laryngoscope (DLS).

METHODS

A total of 53 adult patients, ASA physical status I-II, scheduled for elective plastic surgery under general anesthesia requiring the orotracheal intubation, were randomly allocated to either DLS or ILMA groups. After a standard intravenous anesthesia induction, orotracheal intubation was performed. Noninvasive blood pressure and heart rate were recorded before (baseline values) and after anesthesia induction (post-induction values), at intubation and every minute for the first 5 minutes after intubation. The data were analyzed using Chi-square test, paired and unpaired Student's t test, and repeated-measures analysis of variance as appropriate.

RESULTS

The mean intubation time in the ILMA group was longer than that in the DLS group (P < 0.05). The blood pressure and heart rate increased significantly after intubation in the two groups compared to the post-induction values (P < 0.05), but the maximum value of blood pressure during the observation did not exceed the baseline value, while the maximum value of heart rate was higher than the baseline (P < 0.05). During the observation, there were no significant differences in blood pressure and heart rate among each time point and in the maximum values between the two groups.

CONCLUSIONS

Orotracheal intubations by using ILMA and DLS produce similar hemodynamic response. ILMA has no advantage in attenuating the hemodynamic responses to orotracheal intubation compared with DLS.

摘要

背景

插管喉罩气道(ILMA)为经口气管插管提供了一种新方法,预计其产生的心血管应激反应较小。然而,现有研究结果并不一致。本研究的目的是确定使用ILMA和直接喉镜(DLS)进行经口气管插管时,血流动力学反应是否存在临床相关差异。

方法

总共53例ASA身体状况为I-II级、计划在全身麻醉下行择期整形手术且需要经口气管插管的成年患者,被随机分配至DLS组或ILMA组。在标准静脉麻醉诱导后,进行经口气管插管。记录麻醉诱导前(基线值)、麻醉诱导后(诱导后值)、插管时以及插管后前5分钟每分钟的无创血压和心率。数据采用卡方检验、配对和非配对t检验以及适当的重复测量方差分析进行分析。

结果

ILMA组的平均插管时间长于DLS组(P<0.05)。与诱导后值相比,两组插管后血压和心率均显著升高(P<0.05),但观察期间血压最大值未超过基线值,而心率最大值高于基线(P<0.05)。观察期间,各时间点的血压和心率以及两组间的最大值均无显著差异。

结论

使用ILMA和DLS进行经口气管插管产生相似的血流动力学反应。与DLS相比,ILMA在减轻经口气管插管的血流动力学反应方面无优势。

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