Verdel André
Laboratoire de Biologie Moléculaire et Cellulaire de la Différenciation, INSERM 309, Institut Albert Bonniot, 38706, La Tronche, France.
Mol Cell. 2006 Jun 23;22(6):709-710. doi: 10.1016/j.molcel.2006.06.004.
HP1 is well known as a key silencing protein. However, in the June 9 issue of Molecular Cell, report that Swi6/HP1 recruits an antisilencing protein, Epe1, to facilitate transcription, leading to a model in which Swi6/HP1 is used as a platform to recruit both silencing and antisilencing activities.
HP1作为一种关键的沉默蛋白而广为人知。然而，在6月9日的《分子细胞》杂志上，有报道称Swi6/HP1招募了一种抗沉默蛋白Epe1来促进转录，从而形成了一种模型，即Swi6/HP1被用作一个平台来招募沉默和抗沉默活性。
