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支气管源性癌的化疗管理:使用氨基二醇的一种新型甲磺酸酯NSC-140117进行的试验

Chemotherapeutic management of bronchogenic carcinoma: trials with NSC-140117, a new methanesulfonic acid ester of aminoglycol.

作者信息

Gad-el-Mawia N, Mahmoud M, Osman A, El-Morsi B, El-Merzabani M M, Aboul-Enein M, Sakurai Y

出版信息

Cancer Chemother Rep. 1975 Mar-Apr;59(2 Pt 1):367-70.

PMID:167937
Abstract

A new drug, NSC-140117, was used in the management of 15 patients who had late bronchogenic carcinoma and were unable to receive surgical or radiotherapeutic treatment. Good responses in the form of 90% shrinkage in the size of the lesionswere encountered in nine patients (60%). Response is still being maintained from 6 months to 1.5 years after the start of therapy. No toxic effects, including hematopoietic toxicity, were encountered.

摘要

一种新药NSC - 140117被用于治疗15例晚期支气管源性癌患者,这些患者无法接受手术或放射治疗。9例患者(60%)出现了良好反应,表现为病灶大小缩小90%。治疗开始后6个月至1.5年,反应仍在维持。未出现包括造血毒性在内的毒性作用。

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1
Chemotherapeutic management of bronchogenic carcinoma: trials with NSC-140117, a new methanesulfonic acid ester of aminoglycol.支气管源性癌的化疗管理:使用氨基二醇的一种新型甲磺酸酯NSC-140117进行的试验
Cancer Chemother Rep. 1975 Mar-Apr;59(2 Pt 1):367-70.
2
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