LaCasce Ann S
Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.
Oncologist. 2006 Jun;11(6):674-80. doi: 10.1634/theoncologist.11-6-674.
Post-transplant lymphoproliferative disorder is the most common malignancy, with the exception of skin cancer, after solid organ transplantation in adults. The incidence varies according to the transplanted organ and is often associated with Epstein-Barr virus. Prognosis is variable, due in part to the heterogeneity of the disease, which ranges from reactive plasmacytic hyperplasia to aggressive monoclonal disease.
移植后淋巴细胞增生性疾病是成人实体器官移植后除皮肤癌外最常见的恶性肿瘤。其发病率因移植器官而异,且常与 Epstein-Barr 病毒相关。预后各不相同,部分原因是该疾病具有异质性,范围从反应性浆细胞增生到侵袭性单克隆疾病。