Yaguchi N, Okubo Y, Takeda M, Wakabayashi T, Handa K, Sekiguchi M
First Department of Internal Medicine, School of Medicine, Shinshu University, Matsumoto.
Nihon Kyobu Shikkan Gakkai Zasshi. 1991 May;29(5):595-9.
A 55-year-old male was admitted with non productive cough and fever which had continued for 6 weeks. The patient had symptoms of peripheral neuralgia. Chest X-ray revealed bilateral hilar lymphadenopathy (BHL) and reticular shadows in both lung fields. Other laboratory abnormalities included hematuria, RBC cast, high BUN, leukocytosis and thrombocytosis. Destruction of the internal membrane of arterioles was observed in a livedo reticularis on the right lower extremity. Renal angiography showed irregularity in the diameter, discontinuation and narrowing of peripheral arteries of both kidneys. These findings suggested the existence of "angiitis". These data were compatible with the diagnosis of polyarteritis nodosa (PN). Prednisolone (60 mg/day) administration resulted in the improvement of his symptoms and laboratory findings. A case of PN with lymph node swelling has been reported, however PN with BHL has not yet been reported. This is the first report of PN with BHL.
一名55岁男性因持续6周的干咳和发热入院。患者有周围神经痛症状。胸部X线显示双侧肺门淋巴结肿大(BHL)以及双肺野网状阴影。其他实验室异常包括血尿、红细胞管型、高尿素氮、白细胞增多和血小板增多。在右下肢的网状青斑中观察到小动脉内膜破坏。肾血管造影显示双肾外周动脉直径不规则、中断和狭窄。这些发现提示存在“血管炎”。这些数据与结节性多动脉炎(PN)的诊断相符。给予泼尼松龙(60毫克/天)后,患者症状和实验室检查结果有所改善。虽然有报道过伴有淋巴结肿大的PN病例,但伴有BHL的PN尚未见报道。这是首例伴有BHL的PN报道。