Kusumoto Fred, Goldschlager Nora
Electrophysiology and Pacing Service, Division of Cardiology, Department of Medicine, Mayo Clinic, Jacksonville, Florida 32224, USA.
Clin Cardiol. 2006 Jun;29(6):237-42. doi: 10.1002/clc.4960290603.
Implantable cardiac devices have become firmly entrenched as important therapeutic tools for a variety of cardiac conditions. The second part of this two-part review discusses the contemporary use and follow-up of implantable cardioverter defibrillators (ICD) and the implantable loop recorder. The ICD has become the standard therapy for protecting patients against sudden cardiac death. Two recent trials, the Multicenter Automatic Defibrillator Trial II (MADIT II) and the Sudden Cardiac Death Heart Failure Trial (SCD-HEFT), demonstrated that the ICD is associated with a significant survival benefit for patients with reduced ejection fraction (< 0.30-0.35), particularly if heart failure symptoms are present. The ICD has an important role in the management of other conditions associated with a high risk for sudden death, such as hypertrophic cardiomyopathy, long QT syndrome, and Brugada syndrome. The implantable loop recorder has become an important diagnostic tool for the patient with unexplained syncope.
植入式心脏设备已牢固确立为治疗多种心脏疾病的重要治疗工具。这篇分两部分的综述的第二部分讨论了植入式心脏复律除颤器(ICD)和植入式环形记录仪的当代应用及随访情况。ICD已成为保护患者预防心源性猝死的标准治疗方法。最近的两项试验,即多中心自动除颤器试验II(MADIT II)和心源性猝死心力衰竭试验(SCD-HEFT),表明ICD对射血分数降低(<0.30-0.35)的患者具有显著的生存益处,尤其是在存在心力衰竭症状的情况下。ICD在管理其他与猝死高风险相关的疾病中也发挥着重要作用,如肥厚型心肌病、长QT综合征和Brugada综合征。植入式环形记录仪已成为不明原因晕厥患者的重要诊断工具。