Shah V S, Ananth A, Sohal G K, Bertges-Yost W, Eshelman A, Parasuraman R K, Venkat K K
Henry Ford Hospital, Detroit, Michigan 48202, USA.
Transplant Proc. 2006 Jun;38(5):1283-5. doi: 10.1016/j.transproceed.2006.03.027.
An ideal method for quality of life (QOL) assessment in renal transplant recipients (RTR) has not yet been determined. Present assessments of QOL in RTR are lengthy, cumbersome to administer, and difficult to interpret. We used a previously validated single question QOL scale score (QLS) that directly asks about the patients' overall assessment of their QOL; "Considering all parts of my life-physical, emotional, social, spiritual, and financial--over the past 2 days the quality of my life has been ... ". The QLS ranges from 0 ("very bad") to 10 ("excellent"). Patients were contacted prior to their routine office visit when they were free of acute medical problems. Fifty RTR participated. Psychosocial and medical variables included the Beck Depression Inventory, Illness Effects Questionnaire, Multidimensional Scale of Perceived Social Support, time since transplant, age, creatinine, hemoglobin, and albumin levels. Of the patients, 64% were African-American and 48% were women; 94% of patients had a score>5. Mean QLS was 7.5+/-2.3. Perception of a better QOL correlated with less perception of depression and illness effects and with perception of greater social support and satisfaction with life (all P<.05). Perception of QOL did not correlate with age, time since transplantation, creatinine, hemoglobin or albumin levels. We concluded that QLS is a quick tool to measure subjective QOL in RTR for correlation with psychosocial factors of interest in this group. These studies should be replicated in larger multiethnic populations.
肾移植受者（RTR）生活质量（QOL）评估的理想方法尚未确定。目前对RTR生活质量的评估冗长、实施繁琐且难以解读。我们使用了先前验证过的单问题生活质量量表评分（QLS），该评分直接询问患者对其生活质量的总体评估；“考虑到我生活的各个方面——身体、情感、社会、精神和经济——在过去两天里，我的生活质量是……”。QLS的范围从0（“非常差”）到10（“优秀”）。在患者进行常规门诊就诊且无急性医疗问题时与他们联系。50名RTR参与了研究。心理社会和医学变量包括贝克抑郁量表、疾病影响问卷、感知社会支持多维量表、移植后的时间、年龄、肌酐、血红蛋白和白蛋白水平。患者中，64%是非裔美国人，48%是女性；94%的患者评分>5。QLS的平均值为7.5±2.3。对更好生活质量的感知与较少的抑郁和疾病影响感知以及更大的社会支持感知和生活满意度相关（所有P<0.05）。生活质量感知与年龄、移植后的时间、肌酐、血红蛋白或白蛋白水平无关。我们得出结论，QLS是一种快速测量RTR主观生活质量的工具，可用于与该组感兴趣的心理社会因素进行关联。这些研究应在更大的多民族人群中重复进行。
