On the bias in HI titers and how to reduce it.
作者信息
Nauta Jozef J P, de Bruijn Iris A
机构信息
Solvay Pharmaceuticals, Clinical Development Influenza Vaccines, P.O. Box 900, 1380 DA Weesp, The Netherlands.
出版信息
Vaccine. 2006 Nov 10;24(44-46):6645-6. doi: 10.1016/j.vaccine.2006.05.052. Epub 2006 Jun 6.
Abstract
HI titers measure anti-HA antibody concentrations in sera. By the way they are defined standard titers underestimate the true amounts of antibody. A new definition is proposed, the mid-value definition. Under mild conditions mid-value titers are on average closer to the true value than standard titers.
摘要
Zotero 插件