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急性酒精使用与非致命伤害的多中心研究:来自世界卫生组织酒精与伤害合作研究的数据。

Multicentre study of acute alcohol use and non-fatal injuries: data from the WHO collaborative study on alcohol and injuries.

作者信息

Borges Guilherme, Cherpitel Cheryl, Orozco Ricardo, Bond Jason, Ye Yu, Macdonald Scott, Rehm Jürgen, Poznyak Vladimir

机构信息

Instituto Nacional de Psiquiatria & Universidad Autónoma Metropolitana-Xochimilco, Calzada Mexico Xochimilco No. 101, Col. San Lorenzo Huipulco, Mexico DF 14370.

出版信息

Bull World Health Organ. 2006 Jun;84(6):453-60. doi: 10.2471/blt.05.027466. Epub 2006 Jun 21.

Abstract

OBJECTIVES

To study the risk of non-fatal injury at low levels and moderate levels of alcohol consumption as well as the differences in risk across modes of injury and differences among alcoholics.

METHODS

Data are from patients aged 18 years and older collected in 2001-02 by the WHO collaborative study on alcohol and injuries from 10 emergency departments around the world (n = 4320). We used a case-crossover method to compare the use of alcohol during the 6 hours prior to the injury with the use of alcohol during same day of the week in the previous week.

FINDINGS

The risk of injury increased with consumption of a single drink (odds ratio (OR) = 3.3; 95% confidence interval = 1.9-5.7), and there was a 10-fold increase for participants who had consumed six or more drinks during the previous 6 hours. Participants who had sustained intentional injuries were at a higher risk than participants who had sustained unintentional injuries. Patients who had no symptoms of alcohol dependence had a higher OR.

CONCLUSION

Since low levels of drinking were associated with an increased risk of sustaining a non-fatal injury, and patients who are not dependent on alcohol may be at higher risk of becoming injured, comprehensive strategies for reducing harm should be implemented for all drinkers seen in emergency departments.

摘要

目的

研究低水平和中等水平饮酒时非致命伤害的风险,以及不同伤害方式的风险差异和酗酒者之间的风险差异。

方法

数据来自于2001 - 2002年世界卫生组织关于酒精与伤害的合作研究中收集的18岁及以上患者,这些患者来自全球10个急诊科(n = 4320)。我们采用病例交叉法,将受伤前6小时内的酒精使用情况与前一周同一工作日的酒精使用情况进行比较。

研究结果

单次饮酒会增加受伤风险(优势比(OR)= 3.3;95%置信区间 = 1.9 - 5.7),在过去6小时内饮用6杯或更多酒的参与者受伤风险增加了10倍。遭受故意伤害的参与者比遭受非故意伤害的参与者风险更高。没有酒精依赖症状的患者优势比更高。

结论

由于低水平饮酒与非致命伤害风险增加有关,且不依赖酒精的患者可能受伤风险更高,因此应对在急诊科就诊的所有饮酒者实施全面的减少伤害策略。

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