Kumar Bhushan, Narang Tarun, Gupta Somesh, Gulati Madhu
Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Sex Health. 2006 May;3(2):113-8. doi: 10.1071/sh05031.
Peyronie's disease is a localised connective tissue disorder that involves the tunica albuginea of the penis. Although long recognised as an important clinical entity of the male genitalia, the aetiology of this disease has remained poorly understood.
The epidemiology and clinical presentation of Peyronie's disease during a 10-year period was evaluated.
Forty-two men with Peyronie's disease from Chandigarh, India were reviewed retrospectively. The prevalence of Peyronie's patients was 1.97/1000 patients. Their ages ranged from 23 to 70 years. Most of them presented during the early phase of the disease. The most common presenting complaint was penile curvature in 34 (80.95%) followed by pain on erection in 28 (66.66%). History of penile trauma was revealed by four (9.52%) patients. Among the risk factors, hypercholesterolemia (60%), hypertension (33.3%) and asymptomatic hyperuricemia (28.34%) were the most common. Twenty-two patients with Peyronie's disease were studied by ultrasonography. Ultrasonogram was more accurate than clinical assessment in delineating the extent of lesions. In one-third of the patients, sonography demonstrated the plaques to be more extensive than had been detected by clinical examination.
The clinical symptoms and signs in our study were, in general, similar to those found in the previous studies. Higher incidence of hypertension and diabetes in patients with Peyronie's disease may also be to an extent due to patients being in an older age group.
佩罗尼氏病是一种局限性结缔组织疾病，累及阴茎白膜。尽管长期以来一直被认为是男性生殖器的重要临床病症，但该疾病的病因仍知之甚少。
对10年间佩罗尼氏病的流行病学和临床表现进行评估。
对来自印度昌迪加尔的42例佩罗尼氏病男性患者进行回顾性分析。佩罗尼氏病患者的患病率为1.97/1000。他们的年龄在23至70岁之间。大多数患者在疾病早期就诊。最常见的主诉是阴茎弯曲，有34例（80.95%），其次是勃起疼痛，有28例（66.66%）。4例（9.52%）患者有阴茎外伤史。在危险因素中，高胆固醇血症（60%）、高血压（33.3%）和无症状高尿酸血症（28.34%）最为常见。对22例佩罗尼氏病患者进行了超声检查。在确定病变范围方面，超声检查比临床评估更准确。在三分之一的患者中，超声检查显示斑块比临床检查发现的更广泛。
我们研究中的临床症状和体征总体上与先前研究中发现的相似。佩罗尼氏病患者中高血压和糖尿病的较高发病率在一定程度上也可能归因于患者年龄较大。
