Lüderitz Berndt
Medizinische Klinik und Poliklinik II, Universitätsklinikum Bonn.
Med Klin (Munich). 2006 Mar 22;101 Suppl 1:147-9.
The treatment of atrial fibrillation still remains challenging in everyday practice. Even after the introduction of catheter ablation, the decision making about the type of therapy became more complex. The recently published guidelines of the American Heart Association, the American College of Cardiology, and the European Society of Cardiology clearly show therapeutic approaches for different types of atrial fibrillation. The fear of thromboembolism still forces the physician to restore sinus rhythms and perform a perfect anticoagulation. Based on large studies, we are able to decide for each patient individually whether oral anticoagulation or acetylsalicylic acid/clopidogrel are required. Future studies in a large cohort of patients are still necessary to clarify the value of interventional therapy in conjunction with antiarrhythmic drug therapy. These will provide patients with a safe therapy and high quality of life despite presenting paroxysmal or persistent atrial fibrillation.
在日常临床实践中,心房颤动的治疗仍然具有挑战性。即使在引入导管消融术后,关于治疗类型的决策也变得更加复杂。美国心脏协会、美国心脏病学会和欧洲心脏病学会最近发布的指南明确显示了针对不同类型心房颤动的治疗方法。对血栓栓塞的担忧仍然迫使医生恢复窦性心律并进行完善的抗凝治疗。基于大量研究,我们能够为每位患者单独决定是否需要口服抗凝药或阿司匹林/氯吡格雷。未来仍有必要对大量患者进行研究,以阐明介入治疗联合抗心律失常药物治疗的价值。尽管存在阵发性或持续性心房颤动,这些研究将为患者提供安全的治疗方法和高质量的生活。